HT-29-Luc

HT-29 Luciferase Cell Line engineered for stable, high-efficiency expression of the luciferase gene.This advanced tool delivers exceptionally high imaging quality and precise, quantifiable luminescence, ensuring your data is both robust and publication-ready.
Designed for versatility, the HT-29 Luciferase Cell Line seamlessly adapts to a broad spectrum of applications—from promoter activity assays and mammalian two-hybrid studies to sophisticated in vivo imaging.
HT-29 cell line was isolated from primary tumors in 1964 by FoghJ using transplantation culture methods and F12 medium containing 15% FBS. Recently, the established cultured cells have been cultured in serum-containing McCoy's 5a medium. This cell line forms tumors in nude mice and also in steroid-treated hamsters. The cells can synthesize IgA, CEA, TGFβ binding protein, and mucin; express urokinase receptor, but no plasma proenzyme activity was detected; do not express CD4, but express galactosylceramide on the cell surface (a possible alternative receptor for HIV). This cell line is positive for oncogenes c-myc, K-ras, H-ras, N-ras, Myb, sis, and fos.