MC38-Luc

MC38 Luciferase Cell Line engineered for stable, high-efficiency expression of the luciferase gene.This advanced tool delivers exceptionally high imaging quality and precise, quantifiable luminescence, ensuring your data is both robust and publication-ready.
Designed for versatility, the MC38 Luciferase Cell Line seamlessly adapts to a broad spectrum of applications—from promoter activity assays and mammalian two-hybrid studies to sophisticated in vivo imaging.
MC38 cell line derived from the colon adenocarcinoma cell line of C57BL/6 mice, are widely used as a mouse model in colorectal cancer research. This cell line exhibits a high mutation rate, particularly in terms of mutanome (mutational profile) and neoantigen (new antigen) expression, making them highly sensitive to immune checkpoint inhibitor therapy.